Derek “Big House” O’Brien is a Texas-style blues guitarist, sometime bassist and record producer based in Austin, TX.

A stalwart of the house band at the famous Austin blues club Antone’s Nightclub, O’Brien is most often found backing up other Austin frontmen, including Delbert McClinton, Lou Ann Barton, The Texas Tornados and almost anyone recording on the Antone’s Records label.

O’Brien has also backed up major blues names such as Buddy Guy and Muddy Waters. Ted Drozdowski, writing on Gibson Guitars’ website, says, “O’Brien has a terse, arrow-sharp and spare style comparable to Jimmie Vaughan’s – light on flash, but soooo right. Check it out.”